They make comics. Lots of comedy is about trying to find a balance between what is offensive and what people are willing to laugh at.
If you're creating humorous content, then you by necessity cross the boundary into the offensive (but you don't necessarily publish it!) as part of the creative process. Otherwise you'll never strike the best balance.
If you're familiar with the webcomic or the blog, you'd recognize that this is probably a reference to off-color language and humor that undoubtedly is typical of their work environment. This doesn't actually offend me at all, but the rest of the job posting does.
Comedians tend to offend once in a while, it's part of the gig. And PA is smack in the middle of the comedy/video game business, sometimes they might trample your delicate sensibilities[1].
As someone who isn't easily offended, that sounds a hundred times better than working in a constant state of fear that you're not being PC enough. But, to each his/her own. At least they're upfront about it, so potential candidates know what they're getting into. Doesn't sound like the environment you want? Don't apply.
For example, I will work for you under the understanding that I will keep giving you shit about the "dickwolves" thing until you finally understand what you did wrong -- and no, you don't have to give your kids' entire college savings away to charity.
"I am an absolute moral authority. Apologizing and shutting up is the only acceptable response when I am pissed off. Any protestation will be taken as further evidence of your complicity."
Or maybe you're just a self-centred special snowflake.
"I'm happy with the status quo, so I'm going to write condescending remarks that could equally apply to anyone who has ever felt the need to stand up for somebody else."
I assume what they mean by that is the work environment will resemble what they've put on camera in their PA TV and other series. It will probably be both more mundane and more "offensive" than what is shown on screen, so the goal would be to find someone that can handle the situation.
"- You should have no problems working in a creative and potentially offensive environment."