"We also looked at different types of psychedelics and didn’t see any systematic differences there."
This was the most fascinating finding to me. I really wouldn't have expected Salvia, Acid, Shrooms, etc. to all produce the same hallucinations ... but I guess ultimately they're all operating on the same core neurochemicals, so I guess it makes sense.
This. There’s obvious differences in salvinorin and psilocybin effects and both are well represented in the data. But keep in mind the current paper only looks at existing categories of visual effect. The second study might include a finer taxonomy.
They don't, they are drastically different in character. There are close similarities within classes between some of the lysergamides, substituted phenethylamines or tryptamines. But even closely structurally related analogues can be extremely different (ex. 2C-E vs DOET vs 2C-C).
LSD is almost nothing like psilocybin or mescaline or DMT. And nothing is like salvinorin...
At low doses they're pretty similar. Moving patterns in wood grain, breathing objects, faintly fractalesque structures. When you take more they get fairly different.
This was the most fascinating finding to me. I really wouldn't have expected Salvia, Acid, Shrooms, etc. to all produce the same hallucinations ... but I guess ultimately they're all operating on the same core neurochemicals, so I guess it makes sense.