I used Apple keyboards for, um, about a decade, so I am very habituated to fn on the left and arrows on the right for page up / page down / home / end.
I have bound fn + the asdf row to switch virtual desktops / spaces, and left fn is convenient for a one-handed space warp.
Yeah I must say, have got quite used to this arrangement now and this has started to feel natural to me after almost a year of using the MacBook keyboard. Kind of perfect layout for me with the full height function row with media keys and the inverted-T arrow buttons.
I have bound fn + the asdf row to switch virtual desktops / spaces, and left fn is convenient for a one-handed space warp.