You can always be laid off. The chances are much higher if you work on things unrelated to the core business at a startup that is losing money (or worse, not making money).

Obviously, if you're the junior hire on a team of 1,000 people doing third-derivative things that relate to revenue, YMMV.

It's also the case that things change to the point where "strategic" people become less strategic for any number of reasons (the company changes, they're "rich and tired" to use a marvelous phrase from a colleague, etc.). Under what's been normal circumstances at Big Tech until recently companies often keep such people around anyway because they're probably the sort of people who can be pretty effective fixers with a half-day of work and such people may be happy to keep collecting a bunch of money. But a lot of companies are scrutinizing more today.