Hacker Newsnew | past | comments | ask | show | jobs | submitlogin

They are looking for antibodies to the spike protein on COVID-19. So if a person has those, then it's proof that they've been exposed to it.

Antibodies are unique for each virus, but there can be "cross-reactivity" where an antibody for a different virus also binds to COVID-19.

Yes, it is possible that there are people out there who have antibodies that bind to COVID-19, who have never been infected with it, but rather have an antibody that cross-reacts with COVID-19. But it would be a very rare occurrence.

So having COVID-19 antibodies isn't a perfect was to tell if a person has been exposed, but it's a very good way to do it since antibodies is highly correlated with exposure.



Would antibodies that can attach to COVID-19 but were produced from a different viral infection potentially make you immune to COVID-19?


I think that is the holy grail.


Yes.

It’s similar to the AAV (adeno-associated virus), a common virus.

There are multiple subtypes, but often an antibody to one will bind to other variants, making you immune.


That was the case with Smallpox and Cowpox, and the original vaccine.


Interesting! From the smallpox wikipedia page:

> The term vaccine derives from the Latin word for cow, reflecting the origins of smallpox vaccination.




Consider applying for YC's Summer 2026 batch! Applications are open till May 4

Guidelines | FAQ | Lists | API | Security | Legal | Apply to YC | Contact

Search: