It's tough for many publishers to find the right ad solution because their traffic, audience, and level of involvement in the business differ.
I work at isocket and want to point out that BuySellAds is great for some people. If you're looking to sell month-long tenancy campaigns on a subscription (pay-until-they-cancel) basis, BSA is the best tool for the job. And for that service, they'll assess a 25% commission on all the ad revenue you generate.
If you're looking more flexibility in your ad packages - CPM, daily/weekly/monthly campaigns, grids, takeovers and a flat fee pricing, you might want to look at isocket. See http://www.isocket.com/group/techcrunch for an example. We're about to release a "free-until-your-first-sale" program so there's essentially no risk in trying us out.
If you've got more questions, feel free to reach out to me at jason@isocket.com.
