Not really. The proportions of fructose and glucose are similar - actually worse if you buy Lustig's theory that the fructose is the most harmful part of sugar and HFCS. Sucrose is quickly broken down into sucrose and fructose - according to Lustig there's no clinically important difference between sucrose and HFCS. I doubt that a little bit of maltose makes much difference, antimicrobial effects aren't going to save you from diabetes, and the results of clinical trials for antioxidants have been underwhelming - they aren't going to save you from diabetes or metabolic syndrome.
Honey is just more unhealthy crap, even if it's natural. Same with agave juice. Sugar is sugar.
Honey is about 40% fructose, 30% glucose, along with sucrose and maltose. It's also known to have antimicrobial and antioxidant effects.
Equating high fructose corn syrup with honey is a major oversimplification.