The QUEST Kodiak is filling in for many of the larger NGOs. I believe it was designed for that express purpose (taking over where the small avgas powered planes could no longer operate due to the price or availability of avgas).
Unfortunately Turboprops come with a whole new set of maintenance requirements but otherwise it's an excellent aircraft and working out quite well.
I think the Quest Kodiak is a great aeroplane, and very comparable to the Cessna 208. Both have many advantages over the Cessna 206s and 210s which were fulfilling these types of roles over the previous 40 years.
The biggest issues with both of these is the cost to buy and also the cost to maintain. Both are well in excess of the older Cessnas.
Unfortunately Turboprops come with a whole new set of maintenance requirements but otherwise it's an excellent aircraft and working out quite well.