Hacker Newsnew | past | comments | ask | show | jobs | submitlogin

Stimulants work because ADHD brains have whacked out dopamine regulation. Stimulants help smooth out the peaks and valleys associated with ADHD. Hyperfocus = overstimulated by dopamine, inattentiveness = understimulated. Taking a stimulate provides a consistent baseline level to help reduce the extremes.


Stimulants work because they activate the underperforming portions of the prefrontal cortex related to attention management.

Chalking it up to dopamine is a gross simplification.

Adderal, for example, stimulates the release / reduces the re-uptake of dopamine, norepinephrine, epinephrine, serotonin, histamine, and CART peptides.




Guidelines | FAQ | Lists | API | Security | Legal | Apply to YC | Contact

Search: