Is guix as rough on the edges as nix? I have nixos installed in qemu, but so far don't find the experience to be pleasant. The ideas are great though, definitely the direction to move for all package managers.
I've no experience with Nix, but I tried guix package manager and it was fine. I didn't hit any edge cases, but I didn't dive deep. I tried installing GuixSD (the OS) too, but failed, and because I was in a hurry, couldn't investigate much. But I did hit a critical issue: scarse docs. It's nowhere near FreeBSD where docs indeed help you out without a google search.