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> Without any Pokémon-specific optimization, Step 5 Preview has so far sustained progress for more than 3,000 turns and 6 million tokens of interaction. By turn 3,082, it had unlocked Cut, earned three Gym Badges, and defeated Lt. Surge. The run is now roughly one-third of the way through the main story.

Finally FireRed is being used as a benchmark again! I believe Astra can beat it in 18 hours. Not sure how that compares.


> They identified two different brain progenitor cells. One, which expresses a gene called Otx2, is destined to become the forebrain and midbrain. The other, which expresses a gene called Gbx2, is committed to forming the hindbrain. They showed that these two cell populations never overlap; they are mutually exclusive from the earliest stages of development.

Very cool. Never thought the brain could have two completely different ancestors


Fun fact: the hindbrain progenitor cell is shaped like a little lizard.

Like the thought:) But actually have read that the hypothesis that the hindbrain (or lower brain) had evolved directly from our lizard ancestors while the upper brain (which does more complex types of thought) evolved later turned out to be wrong. Like the study has shown, they evolved at the same time, and many animals had both. It's just in humans, the upper brain evolved much larger in proportion to the lower brain.

https://thebrainscientist.com/2018/04/11/you-dont-have-a-liz...

But yeah, evolution is fascinating.


The lizard brain, not because it resembles the brain of a lizard, but because it's made up of a trillion tiny lizards

I bet you can tune hyperparameters on the MRI so that the resulting image makes the lizard brain look like a lizard, too.

Because they are proudly causing animalistic, degenerate behavior like Lizzo.

and from another post on the front page right now https://news.ycombinator.com/item?id=49735541 :

"Nervous systems are typically defined as networks of neurons that communicate across synapses. But Burkhardt’s lab found something unique in ctenophores: Beneath the animal’s outer surface is a nerve net (pink mesh in this 3D reconstruction) whose neurons are connected by continuous cytoplasm — but with no synapses between them. “I don’t think any other animal has a nervous system like that,” Burkhardt said. Because ctenophores are one of the earliest branches of the animal family tree, the finding indicates that evolution may have crafted nervous systems twice: in ctenophores, and separately in jellyfish and all other animals."


Funny thing when reading that is as a human I read „crafted nervous system twice” like it would be done over a week or two.

We fail to imagine how much time takes to „craft a nervous system”.

Super scary how small are we in big scheme of things.


https://learn.genetics.utah.edu/content/senses/eye/

at one point I learned that it would only take a few hundred thousand years to evolve an eye, and time felt much deeper.


I think the fact that the sentence says we share the nervous system with jellyfish gives a good indication of that.

Why would it be surprising?

All parts of the body are built like this. Otherwise we would be blobs.

Before becoming two parts they probably were part of the same parent protobrain tissue.

If you told me the hindbrain was ectoderm-derived but the forebrain was endoderm-derived, I might raise an eyebrow or two.


> Before becoming two parts they probably were part of the same parent protobrain tissue.

Article says they weren't.


> All parts of the body are built like this.

Please name one other organ that arises from two separate progenitor cell types. If this is common, I have never heard of it.


Well, your heart contains both mesoderm derived cells (enervation) and ectoderm derived cells (musculature).

Bones, guts, many glands, kidneys.

> I think it's really difficult for the AI agents to tell what is crazy and what isn't, so they are picking up this insane culture. (^▽^) I think you're right...next 5 years are going to be one hell of a rollercoaster

Curious do you have this setup or a howto anywhere?

it's an ethereal thing that mr.musk made popular.

Put succinctly, if a mismatch between the timelines of the bonds in the bond markets and the revenue streams occurs, it's a bubble. This increases the risk to current and future AI investments and buildouts. If the mismatch is strong enough, contagion in other sectors/areas of the world can cause a run to security and pop the bubble.

Just because the bond markets 1/2/3/5-year bonds are bloated does that mean the bubble will pop. It just increases the risk.


This is really pretty! Going to take a look at it later on.

If you follow motor oil geek on YouTube, they've started changing the formulations of the premium oils months ago and that's not going to change until 2028 when more American supply comes online

RTO4AI should be a slogan. Or some variant thereof

Still a great skill, but at this point, I just write "I have adhd, can you explain that again" or "I have adhd". Works great for compressing it ELI5, but less dumb

I end my user CLAUDE.md files with:

"- I'm not always going to read every word, so end each summary message with a TLDR of what you found, what you recommend, and what you need from me."

It works really well.

Sol doesn't need it at all.


Another favorite of fine is asking it read something then to tell me any "questions, comments concerns" it has. Great for getting the jist of articles fast.

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