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> Meds can work wonders, AND you can still be depressed. Medicine resolve biological depression. It doesn't resolve situational depression.

It's not quite that simple. You seem to be hinting at the "chemical imbalance" theory of antidepressants, which has been largely debunked. The reality is much more nuanced and complicated.


The chemical imbalance theory is wrong, but that is not a refutation of the idea of biological depression. It just means that one idea about how it works was incorrect.

> You seem to be hinting at the "chemical imbalance" theory of antidepressants, which has been largely debunked

Can you say more?


The "serotonin hypothesis" is largely unfounded. We don't actually know why SSRIs are effective for some people. It's likely more to do with increased neuroplasticity than a shortage of serotonin in the brain.

This is a good study to start with: https://pubmed.ncbi.nlm.nih.gov/35854107/

> The main areas of serotonin research provide no consistent evidence of there being an association between serotonin and depression, and no support for the hypothesis that depression is caused by lowered serotonin activity or concentrations.

Prescribing antidepressants is a shot in the dark. Doctors can't know for sure if you'll respond to them, especially because we don't even really understand how they work.


I remember considering applying for Anthropic about 1.5 years ago because they seemed like a somewhat more ethical AI company. Then I learned about their Palantir partnership and realized it was all just a clever marketing gimmick.

This is the AI we're using to kill people now, surely it won't make any mistakes or confidently target civilians on accident: https://youtube.com/shorts/WxbHtYzBnvo?si=xh4kda_DuNvHFx0L

They literally bombed a school full of girls.

It's irrelevant whether AI "makes any mistakes" or not, there are no morals either way, and people just seem to be desensitised to all of this


I have type 1 diabetes and have a CGM and insulin pump on me at all times. The manufacturers say you shouldn't take them through the scanners, but me and every diabetic I know has never experienced any issues with the devices, so most of us just go through the scanner and then have to be patted down anyway because it picks up the device.

I dread it every time, because when I've tried to inform TSA agents ahead of time about my medical devices (which all the signs tell you to do!) they either ignore me or just tell me to go through. And then when I don't mention it, I frequently get berated on the other side, while they do the swab test for explosives.


Once again, an article about diabetes that shows a complete lack of understanding of the difference between type 1 and 2.

Purely anecdotal, but I'm a senior engineer with about 15 years of experience and a decently impressive resume. In the past, I almost always get to at least the interviewing stage, and have frequently received multiple offers at the same time. Recruiters used to spam me constantly.

I haven't heard from a recruiter in probably 6 months. I recently put my feelers out and applied to a handful of positions I was qualified for, and got rejection letters from all of them.


Try only including your last 2 positions, as most senior staff tend to scare insecure brogrammers. They probably still won't hire, but you will get more interviews.

There are also a lot of people posting fake jobs for feeding LLM datasets, running scams, and bidding down labor costs. =3


They are attempting to pull other actors into the conflict to increase the chaos of the war, and to increase the cost to the US of fighting it. They can't necessarily win an all out war, but they can make it so costly to the US that the already small political capital they have to fight it dries up.

Is this the one in Bahrain?

UAE. Abu Dhabi

And a nice bonus is that Claude is way better than ChatGPT right now anyway

I just changed last night and honestly I can't tell much of a difference.

I'm not really complaining, it seems fine, but I'm not seeing the "way better" part that people keep saying.


I haven't used ChatGPT but I'm a heavy Claude user and today I was discussing the attack on Iran and I mentioned how stupid it was that Iran had no effective air defense when the US and Israel have the #1 and #4 best air forces in the world and it response ended with this which I thought is funny:

"A country that declares "Death to America" and "Death to Israel" multiple times weekly for 45 years probably should have invested in the ability to defend itself against America and Israel."


It's not sycophantic and has a much better "voice."

Not that I’m a friend of OpenAI, but ChatGPT has relatively fine-grained “personalization” options, and it was never sycophantic with the “efficient” tone for me. Rather the opposite, sometimes it seemed slightly indignant when I criticized it.

It definitely is sycophantic, but uses A LOT less emoji, lists and header-paragraph-header structure.

How so, it’s unstable like floating ice.

Very very large floating ice is fairly stable

In contrast, getting through Hyperion was hard for me (some of the character stories I LOVED and some felt like a slog), but I really loved Fall of Hyperion.

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